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J Nutr Sci Vitaminol , 67, 273–282, 2021
The Role of Vitamin D Intake on the Prognosis and Incidence of
Lung Cancer: A Systematic Review and Meta-Analysis
Mingxia Qian1, Jun Lin2, Rongrong Fu3, Shuping Qi1, Xiaojun Fu4 ,
4 2,
Lingling Yuan and Lilin Qian *
1 School of Public Health, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China
2 Emergency Medical Center, Ningbo Yinzhou No. 2 Hospital, Ningbo, Zhejiang, China
3 The First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China
4 Department of General Surgery, HwaMei Hospital, University of Chinese Academy of Sciences,
Ningbo, Zhejiang, China
(Received March 17, 2021)
Summary The correlation between vitamin D intake and lung cancer development is
controversial. This meta-analysis aims to evaluate the relationship between vitamin D and
the prognosis and incidence of lung cancer. A comprehensive database search on PubMed,
Web of Science, EBSCO, and Cochrane Library was carried out from the beginning to
November 2020. Long-term survival and the incidence rate of patients with lung cancer
were the primary outcomes of the study. Ten eligible studies were selected for the meta-anal-
ysis following specific
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