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®
ALLIANCE RELIABILITY AND ENHANCEMENT PROGRAMS
® ®
Waters Alliance HPLC Systems:
Guidelines for Ensuring
Optimum Performance
Introduction
®
Since their introduction in1996, Alliance HPLC systems have become established as the
ultimate standard of performance and reliability in high performance liquid chromatography
(HPLC) systems worldwide. These systems have been successfully used for an ever-
expanding range of applications, including mass spectrometry (MS) detection techniques.
Alliance HPLC Systems - based on the 2695, 2695D, 2795 and 2796 family of Separations
Modules - employ leading-edge engineering design and continued technology improvements
to provide rugged high-performance platforms for HPLC and LC/MS system solutions.
Reliability of such instrumentation is clearly of paramount concern in today’s laboratories,
many of which run in a “24/7” environment that does not tolerate unscheduled system
downtime.
The following documents present guidelines for ensuring that your Alliance HPLC system
consistently performs at the highest level. These guidelines focus on the solvent
management aspects of Alliance system operation. Click any of these links for details:
• Mobile phase considerations (proper preparation and degassing)
• Solvent manager components (sapphire plungers and plunger seals)
• Plunger seal wash
• Check valves
• Performance maintenance
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