CONSORT 2010 Statement Updated Guidelines for Reporting Parallel Group RCT清单正式版本.doc

Annals of Internal Medicine ACADEMIA AND CLINIC CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomized Trials Kenneth F. Schulz, PhD, MBA; Douglas G. Altman, DSc; and David Moher, PhD for the CONSORT Group* The CONSORT (Consolidated Standards of Reporting Trials) state-ment is used worldwide to improve the reporting of randomized, controlled trials. Schulz and colleagues describe the latest version, CONSORT 2010, which updates the reporting guideline based on new methodological evidence and accumulating experience.  Ann Intern Med. 2010;152. For author affiliations, see end of text. For the CONSORT Group contributors to CONSORT 2010, see the Appen-dix, available at . This article was published at on 24 March 2010. Editor’s Note: In order to encourage dissemination of the CONSORT 2010 Statement, this article is freely accessible on and will also be published in BMJ, The Lancet, Obstetrics & Gynecology, PLoS Medicine, Open Medicine, Journal of Clinical Epidemiology, BMC Medi-cine, and Trials. The authors jointly hold the copyright of this article. For details on further use, see the CONSORT Web site (). Randomized, controlled trials, when appropriately de-signed, conducted, and reported, represent the gold stan-dard in evaluating health care interventions. However, ran-domized trials can yield biased results if they lack methodological rigor (1). To assess a trial accurately, read-ers of a published report need complete, clear, and trans-parent information on its methodology and findings. Un-fortunately, attempted assessments frequently fail because authors of many trial reports neglect to provide lucid and complete descriptions of that critical information (2– 4). That lack of adequate reporting fueled the develop-ment of the original CONSORT (Consolidated Standards of Reporting Trials) statement in 1996 (5) and its revision 5 years later (6 – 8). While those statements improved the reporting quality for some randomized, controlled tr