细辛中马兜铃酸炮制脱毒研究.pdf

图谱技术，对炮制前后的细辛的整体成分做了完整的比较和分析。经碱制后细辛的甲醇提 取物部分变化明显。其中马兜铃酸A峰值减少。有两个峰消失。乙酸乙酯提取物部分有两 组峰消失，共有峰峰面积均有减小。环己烷提取物部分无非共有峰，共有峰峰面积减小。 关键词：细辛，马兜铃酸，炮制，脱毒 Asari Studieson aristolochicacidofHerbabyprocessingtechnique reducing Abstract rhizomafromAristolochiaAsarum HerbaAsariiS rootand plant Fr．Schmidt sieboldii var．mandshuricum(Maxim．)Kitag，Asarum Asarunsieboldii earliestlistedinthe”Shen Miq，were NongBenCaoJing”，as effect． qufengsanha-n，wenfeihuaxin，tongqiaozhitong herbalmedicinein Wasrecommended Asoneof63kindsofChinese shortage，Asartun by was the PharmaceuticalAdministrationBureauforfocus thesametime also State developing．At Chinese listedastwo medicinestoour now usedTraditionalMedicine key country,iscommonly for to standardsandtheChinese greatdemand．AccordingBubanchengfangpreparation were176 includeHerbaAsari．Herba summary，thereprescriptions Pharmacopoeia’Sincomplete Asafi aristolochichasrenal and asAristolochiac acid，that toxicity plant，contains all the 31rd AristolochicAcidRenal hascausedturbulenceoverworld．ByMay Toxicity great FDAissueda‘FDAnoticeonhealth—related aristolochicacidin 2000，the plantscontaining and