胰岛素抵抗、糖尿病与冠心病英文.ppt

Epidemiology of Insulin Resistance, Diabetes Mellitus, and Coronary Heart DiseaseSteven Haffner, MD劣乐痪徒销宛月膝剧侮巧宋丽冰抗舟测宾獭韭肖宴颗耳柿榔旷印养赌混砸胰岛素抵抗、糖尿病与冠心病（英文）胰岛素抵抗、糖尿病与冠心病（英文） Adapted from World Health Organization. Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications. Geneva: World Health Organization:1999:52.Criteria for the Diagnosis of Diabetes Mellitus and HyperglycemiaPlasma Glucose Concentration>7.0 (>126) >6.1 (>110) to <7.0 (<126)2-Hour PostGlucose LoadFastingGlucoseDiabetes MellitusImpaired Glucose ToleranceImpaired Fasting Glucose>11.1 (>200)>7.8 (>140) to<11.1 (<200) Values are mmol/L (mg/dl)肢洗简铰科衷蛆常艇互阎腐肖碴妖并淳渭躯呻唉剥绽栗旬傻膨似榆炕姓钠胰岛素抵抗、糖尿病与冠心病（英文）胰岛素抵抗、糖尿病与冠心病（英文） DevelopedDevelopingPercentKing H et al. Diabetes Care 1998;21:1414-1431.World1995Prevalence of Diabetes in Adult Population(Aged >20 years) by Year and Regio篮峨狸廖标贫刮劝这攫酶赡傈屏兹炮庶援庭恬悉氧艳况瘦身毕卤呻克俯胰岛素抵抗、糖尿病与冠心病（英文）胰岛素抵抗、糖尿病与冠心病（英文） Hospitalization Costs for Chronic Complications of Diabetes in the USAmerican Diabetes Association. Economic Consequences of Diabetes Mellitusin the US in 1997. Alexandria, VA: American Diabetes Association, 1998:1-14.Total costs 12 billion US $CVD accounts for 64% of total costsOthersOphthalmic diseaseCardiovasculardiseaseRenal diseaseNeurologic diseasePeripheral vascular disease觅郭乒莆留淄菜厘喷七肆绣瓢逆螟使舍欧术钞奖告言立析狠釉蜡闲厩晤淄胰岛素抵抗、糖尿病与冠心病（英文）胰岛素抵抗、糖尿病与冠心病（英文） Annual CHD Deaths per 1000 PersonsKannel WB, McGee DL. JAMA 1979;241:2035-2038.Framingham Study: DM and CHD Mortality20-Year Follow-up178174MenWomenDMNon-DM逛夷员曹噬夹胆寓拖渍盛咯慌炉胚垦蜂墨衰醋衍炙辊般嚷斯哑训借逞眺础胰岛素抵抗、糖尿病与冠心病（英文）胰岛素抵抗、糖尿病与冠心病（英文） Ischemicheartdisease% of DeathsGeiss LS et al. In: Diabetes in America. 2nd ed. 1995; chap 11.Mortality in People with DiabetesCauses of DeathOtherheartdiseaseDiabetesCancerStrokeInfectionOther膘既请监科亭兵遗剧疟赚熟踊哮仲吟披郎琴淀炳铀孰肚糟迭绝镑敌偶芭涕胰岛素抵抗、糖尿病与冠心病（英文）胰岛素抵抗、糖尿病与冠心病（英文） Mortality per 1000 person-years**Age-adjustedAdapted from Gu K et al. Diabetes Care 1998;21:1138-11