加强流行病学观察性研究报告（STROBE）_解释与阐述.ppt

oPL SMEDICINEStrengthening the Reporting of ObservationalStudies in Epidemiology (STROBE): Explanationand ElaborationJan P. Vandenbroucke1, Erik von Elm2,3, Douglas G. Altman , Peter C. G?tzsche , Cynthia D. Mulrow , Stuart J. Pocock ,4567892,10*Charles Poole , James J. Schlesselman , Matthias Eggerfor the STROBE Initiative1 Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands, 2 Institute of Social & Preventive Medicine (ISPM), University of Bern, Bern,Switzerland, 3 Department of Medical Biometry and Medical Informatics, University Medical Centre, Freiburg, Germany, 4 Cancer Research UK/NHS Centre for Statistics inMedicine, Oxford, United Kingdom, 5 Nordic Cochrane Centre, Rigshospitalet, Copenhagen, Denmark, 6 University of Texas Health Science Center, San Antonio, UnitedStates of America, 7 Medical Statistics Unit, London School of Hygiene and Tropical Medicine, London, United Kingdom, 8 Department of Epidemiology, University of NorthCarolina School of Public Health, Chapel Hill, United States of America, 9 Department of Biostatistics, University of Pittsburgh Graduate School of Public Health, andUniversity of Pittsburgh Cancer Institute, Pittsburgh, United States of America, 10 Department of Social Medicine, University of Bristol, Bristol, United KingdomFunding: The initial STROBEworkshop was funded by theEuropean Science Foundation (ESF).Additional funding was receivedfrom the Medical Research CouncilHealth Services ResearchCollaboration and the NationalHealth Services Research &Development MethodologyProgramme. The funders had no rolein study design, data collection andanalysis, decision to publish, orpreparation of the manuscript.A B S T R A C TMuch medical research is observational. The reporting of observational studies is often ofinsufficient quality. Poor reporting hampers the assessment of the strengths and weaknesses ofa study and the generalisability of its results. Taking into account empirical evidence andth