急性缺血性卒中患者血清胆红素水平与病情严重程度和短期转归的关系论文.pdfVIP

２０１６ ２ ２4 ２ Int J Cerebrovasc Dis, February 2016, Vol.24, No.2 ・ １5７・ ・ ・ 【】 。 120，105。 24 h 、、、， （NationalInstitutes of Health Stroke Scale, NIHSS ），NIHSS <8，≥8。 14 dRankin （modifiedRankinScale,mRS），0~2，>2， 、。 、 （P ＜0.01）（P ＜0.01）。 logistic ，［（odds ratio, OR ）1.855，95％（confidence interval, CI ）1.390~ 2.475；P ＜0.01］、（OR 3.380，95％ CI 1.271~11.901；P ＜0.05）（OR 3.51， 95％ CI 1.062~11.473；P ＜0.01）。 ，（P ＜0.05）， （OR 2.411，95％ CI 0.803~7.243；P >0.05）。 ，，， 。 【】 ；；；；；； Relationship betweenthe serum bilirubinlevelandthe severity of disease and short －term outcome inpatients with ischemic stroke Chen Guodong,Xiao Jin,Liu Binrong, DaiJian,Wang Feng,WuZhiyong, ChuZhaohu Department of Neurology, Ma'anshan Central Hospital Affiliated to Wanan Medical College, Ma'anshan 243000, China (Chen GD,Xiao J, Liu BR, DaiJ, Wang F, Wu ZY); Department of Neurology, the First Affiliated Hospitalof Wanan MedicalCollege,Wuhu241001, China(ChuZH) Corresponding author:ChuZhaohu,Email:812424274@ 【Abstract】 ObjectiveTo investigatetherelationshipbetweentheserum bilirubinlevelandtheseverity of disease and short－term outcome in patient with acute ischemic stroke. Methods A total of 120 consecutive inpatients with acute ischemic stroke were enrolled and 105 healthy subjects at the same time wereused as a control group. The biochemical indicators, such as serum total bilirubin, direct bilirubin, indirect bilirubin,blood lipid, and blood glucose were measured within 24 h after admission. The National Institutes of Health Stroke Scale (NIHSS) was used to assess the neurological deficits on the day of admission.TheNIHSS score <8 was defined as mild stroke and ≥8 was defined as moderate to severe stroke.At dischargeor 14 d after onset,themodified Rankin Scale (mRS) was usedto evaluatetheclinical outcomes,0－2 was defined as good outcome and >2 was defined as poor out