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Improving the Reporting Quality of Nonrandomized Evaluations of Behavioral and Public Health Interventions: The TREND Statement
Don C. Des Jarlais, PhD, Cynthia Lyles, PhD, Nicole Crepaz, PhD, and the TREND Group
Don C. Des Jarlais, PhD, Cynthia Lyles, PhD, Nicole Crepaz, PhD, and the TREND Group
Developing an evidence base for making public health decisions will require using data from evaluation studies with randomized and nonrandomized designs. Assessing individual studies and using studies in quantitative research syntheses require transparent reporting of the study, with suf-ficient detail and clarity to read-ily see differences and similarities among studies in the same area. The Consolidated Standards of Reporting Trials (CONSORT) statement provides guidelines for transparent re-porting of randomized clinical trials.
We present the initial version of the Transparent Reporting of Evaluations with Nonrandomized Designs (TREND) statement. These guidelines emphasize the reporting of theories used and descriptions of intervention and comparison conditions, research design, and methods of adjusting for possible biases in evaluation studies that use nonrandomized designs. (Am J Public Health. 2004;94:361-366)
OVER THE PAST SEVERAL decades, a strong movement toward evidence-based medicine [—3
has emerged. In the context of evidence-based medicine, clinical decisions are based on the best available scientific data rather than on customary practices or the personal beliefs of the health care provider. There is now a parallel movement toward evi-dence-
4 5 based public health prac-tices.” The movement is in-tended to utilize the best available scientific knowledge as the foundation for public health-related decisionmaking.
In the context of evidencebased medicine, the randomized controlled trial (RCT) is usually considered of greatest eviden-tiary value for assessing the effi-cacy of interventions. Indeed, the preference for this design is sufficiently stron
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